Quantification, Variability, and Reproducibility of Basal Skeletal Muscle Glucose Uptake in Healthy Humans Using 18F-FDG PET/CT
نویسندگان
چکیده
منابع مشابه
Extensive skeletal muscle uptake of 18F-FDG: relation to immunosuppressants?
A case of gross skeletal muscle uptake of 18F-FDG during PET is described. The clinical context of immunosuppression after heart and lung transplantation and the absence of any other known association make the former a likely etiologic factor.
متن کاملSimple quantification of skeletal muscle glucose utilization by static 18F-FDG PET.
UNLABELLED Skeletal muscle glucose utilization (SMGU) can be measured by dynamic PET imaging with (18)F-FDG to characterize insulin resistance. The aim of this study was to determine the validity of simple methods to quantify SMGU by static PET imaging. METHODS Ten patients underwent dynamic (18)F-FDG PET of the femoral region during hyperinsulinemic euglycemic clamping. SMGU was determined b...
متن کاملExercise, GLUT4, and skeletal muscle glucose uptake.
Glucose is an important fuel for contracting muscle, and normal glucose metabolism is vital for health. Glucose enters the muscle cell via facilitated diffusion through the GLUT4 glucose transporter which translocates from intracellular storage depots to the plasma membrane and T-tubules upon muscle contraction. Here we discuss the current understanding of how exercise-induced muscle glucose up...
متن کاملEnhanced Stimulation of Glucose Uptake by Insulin Increases Exercise-Stimulated Glucose Uptake in Skeletal Muscle in Humans
In vitro studies have shown that insulin and exercise stimulate glucose uptake in part via distinct mechanisms. We determined whether a high rate of insulinstimulated glucose uptake (good insulin sensitivity) is associated with an enhanced ability of exercise to increase glucose uptake in vivo in humans. In our study, 22 normal subjects performed one-legged isometric exercise for 105 min (45–15...
متن کاملThe effect of glucagon on FDG uptake in skeletal muscle.
Glucagon is used as an anti-motility agent during gastrointestinal tract examinations. We experienced subjects with enhanced 18F-fluorodeoxyglucose (FDG) uptake in whole-body skeletal muscle when conducting positron emission tomography (PET). The subjects had been administered glucagon during gastroscopy just prior to PET. This observation prompted us to perform the present retrospective study ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Nuclear Medicine
سال: 2015
ISSN: 0161-5505,2159-662X
DOI: 10.2967/jnumed.115.159715